Derivatives of benzimidazole in the experiment have teratogenic effect. Primaquine - derived 8aminohinolina. Levamisole (decaris) stimulates the muscles of worms and Nholinoreceptors vyzy-Vaeth their spastic paralysis. The drug is contraindicated during pregnancy and breastfeeding. In addition, praziquantel is effective in trematodozah liver (clonorchiasis, described storhoz). These funds are used in the form of tablets and vaginal suppozi-thorium. As a result, developing spastic paralysis of the worms. Fansidar impatient a combined drug pyrimethamine, and sulfadoxine is prescribed for parasite resistance to chloroquine. Praziquantel (biltritsid) increases the permeability of the membrane of the muscle-curl worms for Ca2 +. Apply mebendazole in ascariasis, enterobioze (pinworms infestation), Anakie lostomidoze, trichuriasis (invasion trichurid) strongiloidoze. Apply piperazine in ascariasis and enterobiasis. Instead of metronidazole can be used tinidazole, ornidazole. For both forms of leishmaniasis are used antimony drugs - sodium stiboglyukonat (solyusurmin, intravenously), and meglumine pentamidine (intramuscularly). Used mainly for prevention of falciparum malaria together with chloroquine. Piperazine - GAMKreceptors agonist, causes hyperpolarization of the membrane of muscle worms, resulting in growing their flaccid paralysis and immobilization. Similar Left Ventricular Ejection Fraction and properties have thiabendazole and Albendazole. When teniasis the drug should only be Pack-years in combination with saline laxatives to prevent possible cysticercosis. Increases the effectiveness of pyrimethamine in combination with sulfonamides. Side effects of drugs of antimony: nausea, vomiting, abdominal pain, violation of the liver, kidneys, myalgia, cough, pain in the breastbone. Distinguish between intestinal and extraintestinal nematodoses, cestodosis and trematodozy. Protivoblastomnymi means known drugs, delay equation describing the development of malignant tumors (cancer, sarcoma, melanoma) and malignant lesions of the blood (leukemias, etc.) impatient . By proguanil is rapidly developing resistance of Plasmodium and is now in many regions of proguanil as an antimalarial tool is not very effective. Side effects of quinine: impatient (ringing in the ears, headache, rasplyvcha-Toe vision, hearing loss, disorientation, nausea, diarrhea, skin impatient rash), dysfunction serdechnososudi-stop system, kidneys, blood system. With the ineffectiveness of other antimalarials against erythro-tsitarnyh forms of plasmodia, especially in the treatment of falciparum malaria, prescribe doxycycline (an antibiotic from the group tetratsik-Linova;), artemisinin (Artemisia alkaloid) or its Derivatives - artemether, artesunate. Ivermectin - tool of choice for strongiloidoze. The body is transformed into an active metabolite tsikloguanil, which inhibits dihydrofolate reductase. Apply niclosamide at teniarinhoze, bothriocephaliasis, hymenolepiasis (less effective than praziquantel). Effective against preeritrotsitarnyh, Erith rotsitarnyh forms of plasmodia and gamontov. By cestodes (tape helminths) is considered bullish (unarmed) and pork (armed) tapeworm (Taenia saginata and T solium), broad tapeworm (Diphyllobotrium latum), dwarf tapeworm (Nutenolepis nana), Echinococcus (Echinococcus granulosis, E multilocularis). In addition, the trichomoniasis with use of nitrofurans, in particular, furazo-Lydon.
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